

Diagnostic & Veterinary
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Biotin methyltetrazine
Descrition & Target
Biotin methyltetrazine reacts with cyclooctene (TCO, methylcyclopropene) containing molecules via copper free click chemistry. This copper free bioorthogonal reaction is useful for labeling live cells, or when there are concerns about native protein function loss with copper in cell extracts. Methyltetrazine has improved chemical stability compared to tetrazine.
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Biotin picolyl azide
Descrition & Target
Biotin picolyl azide reacts with alkyne to form 1,2,3-triazole by 1,3-dipolar Huisgen cycloaddition through the use of a much lower copper (I) concentration without sacrificing reaction efficiency.
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Biotin, Succinimidyl Ester (Biotin SE)
Descrition & Target
Biotin SE (Biotin, succinimidyl ester) is readily coupled to a primary or secondary amine under mild conditions. <ul> <li>White solid soluble in DMSO and moderately soluble in DMF</li> <li>Store at -20°C</li> <li>C<sub>14</sub>H<sub>19</sub>N<sub>3</sub>O<sub>5</sub>S</li> <li>MW: 341.38</li> </ul>
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Biotin-11-CTP, 10 mM in pH 7.5 TE buffer
Descrition & Target
Biotin-11-CTP (Biotin-11-cytidine-5'-triphosphate, tetralithium salt) can be enzymatically incorporated into RNA
<ul>
<li>10 mM solution in pH 7.5 Tris-HCl buffer</li>
<li>Store at -20°C</li>
<li>C<sub>28</sub>H<sub>42</sub>N<sub>7</sub>O<sub>17</sub>P<sub>3</sub>SLi<sub>4</sub></li>
<li>MW: 901.42</li>
</ul>
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Biotin-11-UTP, 1 mM in pH 7.5 Tris-HCl Buffer
Descrition & Target
Biotin-11-UTP can be enzymatically incorporated into RNA.
<ul>
<li>10 mM solution in pH 7.5 Tris-HCl buffer</li>
<li>Store at -20°C</li>
<li>C<sub>28</sub>H<sub>41</sub>N<sub>6</sub>O<sub>18</sub>P<sub>3</sub>SLi<sub>4</sub></li>
<li>MW: 902.5</li>
</ul>
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Biotin-11-UTP, 75 mM in pH 7.5 Tris-HCl Buffer
Descrition & Target
Biotin-11-UTP can be enzymatically incorporated into RNA. The number 11 indicates the number of carbons between biotin and UTP. Supplied as a 75 mM solution in pH 7.5 Tris-HCl buffer; 30 uL.
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Biotin-11-dCTP, 1mM in pH 7.5 TE buffer
Descrition & Target
Biotin-11-dCTP (Biotin-11-2'-deoxycytidine-5'-triphosphate, tetralithium salt) can be enzymatically incorporated into DNA via nick translation, random priming, or 3'-end terminal labeling. The number 11 is the number of atoms in the linker between biotin and dCTP.
<ul>
<li>1 mM solution in pH 7.5 Tris-HCl buffer</li>
<li>Store at -20°C</li>
<li>C<sub>28</sub>H<sub>42</sub>N<sub>7</sub>O<sub>16</sub>P<sub>3</sub>SLi<sub>4</sub></li>
<li>MW: 885.42</li>
</ul>
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Biotin-11-dUTP, 1 mM In Ph 7.5 Tris-HCl
Descrition & Target
Biotin-11-dUTP can be enzymatically incorporated into DNA via nick translation, random priming, or 3'-end terminal labeling. The number '11' is the number of atoms in the linker between biotin and dUTP. 9689c5aa-6556-4b3c-b5d1-1e693715ba07 also offers biotin-16-dUTP and biotin-20-dUTP . The length of the linker affects the incorporation efficiency of the biotin-dUTP probe into DNA using DNA polymerases, and it also affects biotin/avidin or biotin/streptavidin. In general, the shorter the linker, the more efficiently the biotin-dUTP is incorporated into DNA by DNA polymerases. On the other hand, the longer the linker, the better biotin can interact with avidin or streptavidin.
<ul>
<li>1 mM solution in pH 7.5 Tris-HCl buffer</li>
<li>Store at -20°C</li>
<li>C<sub>28</sub>H<sub>41</sub>N<sub>6</sub>O<sub>17</sub>P<sub>3</sub>Sli<sub>4</sub></li>
<li>MW: 886.5</li>
</ul>
Biotin-11-dUTP is also available as a lyophilized solid.
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Biotin-11-dUTP, Lyophilized Powder
Descrition & Target
Biotin-11-dUTP can be enzymatically incorporated into DNA via nick translation, random priming, or 3'-end terminal labeling. The number '11' is the number of atoms in the linker between biotin and dUTP. 9689c5aa-6556-4b3c-b5d1-1e693715ba07 also offers biotin-16-dUTP and biotin-20-dUTP. The length of the linker affects the incorporation efficiency of the biotin-dUTP probe into DNA using DNA polymerases, and it also affects biotin/avidin or biotin/streptavidin. In general, the shorter the linker, the more efficiently the biotin-dUTP is incorporated into DNA by DNA polymerases. On the other hand, a longer linker should facilitate interaction between biotin and avidin or streptavidin.
<ul>
<li>Lyophilized solid more suitable for long term storage. The product contains lyophilized TE buffer.</li>
<li>Store at -20°C</li>
<li>C<sub>28</sub>H<sub>41</sub>N<sub>6</sub>O<sub>17</sub>P<sub>3</sub>Sli<sub>4</sub></li>
<li>MW: 886.5</li>
</ul>
Biotin-11-dUTP is also available as a 1 mM solution in TE buffer.
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Biotin-12, SE
Descrition & Target
Biotin-12 SE is an amine-reactive biotin derivative with a long spacer group. It is useful for making biotin labeled nucleoside triphosphates among other applications. <ul> <li>White solid soluble in DMSO or DMF</li> <li>Store at -20°C</li> <li>C<sub>24</sub>H<sub>37</sub>N<sub>5</sub>O<sub>7</sub>S</li> <li>MW: 539.64</li> </ul>
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Biotin-16-UTP, 10 mM in pH 7.5 Tris-HCl Buffer
Descrition & Target
Biotin-16-UTP (Biotin-16-uridine-5'-triphosphate, tetralithium salt) can be enzymatically incorporated into RNA.
<ul>
<li>10 mM solution in pH 7.5 Tris-HCl buffer</li>
<li>Store at -20°C</li>
<li>C<sub>32</sub>H<sub>48</sub>N<sub>7</sub>O<sub>19</sub>P<sub>3</sub>Sli<sub>4</sub></li>
<li>MW: 987.51</li>
</ul>
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Biotin-16-UTP, 75 mM in pH 7.5 Tris-HCl Buffer
Descrition & Target
Biotin-16-UTP can be enzymatically incorporated into RNA. The number 16 indicates the number of carbons between biotin and UTP. Supplied as a 75 mM solution in pH 7.5 Tris-HCl buffer; 30 uL.
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