Diagnostic & Veterinary
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Aminooxy-5(6)-FAM
Descrition & Target
Aminooxy reagents such as aminooxy-5(6)-FAM react with aldehydes or ketones to form a stable hydrazone compound under mild conditions. Similar to ARP, aminooxy-5(6)-FAM can be used to label abasic sites in damaged DNA. <ul> <li>&lamba;<sub>Ex</sub>/&lamba; <sub>Em</sub>(pH 9) = 494/521nm</li> <li>Orange solid soluble in DMF, DMSO, or pH >6.5 buffers</li> <li>Store at -20°C and protect from moisture and light</li> <li>C<sub>26</sub>H<sub>21</sub>F<sub>3</sub>N<sub>2</sub>O<sub>9</sub></li> <li>MW: 562.5</li> </ul>
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Aminooxy-5(6)-ROX
Descrition & Target
Aminooxy-5(6)-ROX reacts with aldehydes or ketones to a stable hydrazone compound under mild conditions. Similar to ARP, aminooxy-5(6)-ROX can be used to label abasic sites in damaged DNA. <ul> <li>&lamba;<sub>Ex</sub>/&lamba;<sub>Em</sub> (MeOH): 568/595 nm</li> <li>Dark purple solid soluble in DMF or DMSO</li> <li>Store at -20°C and protect from moisture and light</li> <li>C<sub>45</sub>H<sub>51</sub>F<sub>6</sub>N<sub>5</sub>O<sub>10</sub></li> <li>MW: 935.90</li> </ul>
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Aminooxy-5(6)-TAMRA
Descrition & Target
Aminooxy-5(6)-ROX reacts with aldehydes or ketones to form a stable hydrazone compound under mild condition. Similar to ARP, aminooxy-5(6)-TAMRA can be used to label abasic sites in damaged DNA. <ul> <li>&lamba;<sub>Ex</sub>/&lamba; <sub>Em</sub>(MeOH) = 540/565 nm</li> <li>Dark red solid soluble in DMF or DMSO</li> <li>Store at -20°C and protect from moisture and light</li> <li>C<sub>36</sub>H<sub>39</sub>F<sub>6</sub>N<sub>5</sub>O<sub>10</sub></li> <li>MW: 815.71</li> </ul>
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Aminooxy-Biotin
Descrition & Target
Aminooxy-biotin can be used to covalently attach biotin to a molecule with an aldehyde or ketone group. The aminooxy group reacts with an aldehyde or ketone group to form a stable oxime linkage in an aqueous solution at neutral pH. The reaction is fast and can be further accelerated by adding aniline as a catalyst. Thus, aminooxy reagents are superior to hydrazide reagents, which also react with aldehydes or ketones but form unstable hydrazone linkages.
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Aminopropargyl dATP [7-Deaza-7-Propargylamino-2'-deoxyadenosine-5'-triphosphate]
Descrition & Target
Aminopropargyl dATP [7-Deaza-7-Propargylamino-2'-deoxyadenosine-5'-triphosphate]
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