Doron scientific is pleased to offer Tetrodotoxin isolated from Tetraodon pardalis. Tetrodotoxin (TTX) is an established potent and selective blocker of some Nav channels.
Tetrodotoxin, A Classic Blocker of a Subset of NaV Channels.
We offer TTX Citrate and TTX (Citrate free).
Source: Natural, Purity: >98%
Availab
le at an extremely attractive price for bulk quantities from 100mg (1mg/vial) up to 1Gram.
Please see information in our website products link below.
Tetrodotoxin citrate TTX CAS 18660-81-6
Description: Na+ channel blocker Purity: >99% (HPLC)
Tetrodotoxin (TTX) is an established potent and selective blocker of some Nav channels. Moreover, TTX sensitivity is used to define subclasses of Nav channels. It is widely used both to probe Nav activity and to reduce or block excitability in neurophysiological preparations.
Special Conditions This product is a toxin.
Contact us via email at: info@doronscientific.com
Product Size and Price
Size 100 x 1mg vial, For a quote Please contact us via email: info@doronscientific.com
Size 250 x 1mg vial, For a quote Please contact us via email: info@doronscientific.com
Size 500 x 1mg vial, For a quote Please contact us via email: info@doronscientific.com
Tetrodotoxin (TTX) is an established potent and selective blocker of some Nav channels. Moreover, TTX sensitivity is used to define subclasses of Nav channels. It is widely used both to probe Nav activity and to reduce or block excitability in neurophysiological preparations.
Doron scientific is pleased to offer Tetrodotoxin (citrate) isolated from Tetraodon pardalis.
Product name: Tetrodotoxin citrate
Description: Na+channel blocker; water-soluble
Biological description: Water soluble citrate salt of tetrodotoxin. Potent, selective and reversible, use-dependent inhibitor of voltage-dependent Na+
Purity> 98%
General notes: To purchase this product and for additional information Please contact customer services via: info@doronscientific.com
Chemical name: Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethano-10aH-[1,3]dioxocino[6,5-d] pyrimidine-4,7,10,11,12-pentol + citrate buffer
Molecular weight: 319.27
Chemical structure:
Molecula formula: C11H17N3O8
CAS Number: 18660-81-6
Storage instructions: Store at -20°C. Store under Desiccating conditions. The product can be stored for up to 12 months.
Solubility overview: Soluble in water
Handling: Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Please contact us via email: info@doronscientific.com
Tetrodotoxin citrate images:
References for Tetrodotoxin citrate 18660-81-6
This product has been referenced in:
Narahashi T et al.Recent advances in the study of mechanism of action of marine neurotoxins.Neurotoxicology 15:545-54 (1994). Read more (PubMed: 7854588) »
Catterall WANeurotoxins that act on voltage-sensitive sodium channels in excitable membranes. Annu Rev Pharmacol Toxicol 20:15-43 (1980). Read more (PubMed: 6247957) »
Kao CYPharmacology of tetrodotoxin and saxitoxin. Fed Proc 31:1117-23 (0). Read more (PubMed: 5032475) »
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