DCDAPH (1,1-dicyano-6-(4-N,N-dimethylaminophenyl)-1,3,5-hexatriene) is a far-red fluorescent probe that has proved to have affinity to A&beta; plaques. It has been used for fluorescent staining of brain sections, as well as <em>in vivo</em> detection of A&beta;_1-42 aggregates by small animal near-IR imaging.  DCDAPH has high affinity (Ki= 37 nM, Kd=27 nM) to A&beta;_1-42 aggregates.
<ul>
<li>Dark purple solid</li>
<li>&lamba;_Ex/&lamba;_Em = 597/665 nm (PBS)</li>
<li>Store at -20°C and protect from light, especially in solution</li>
<li>C16H15N3</li>
<li>MW: 249.31</li>
</ul>