DiBAC₄(3) (Bis-(1,3-Dibarbituric acid)-trimethine oxanol) is a so-called translational membrane potential dye that redistributes within the cell membrane when membrane potential changes. The fluorescence of the dye is enhanced when the dye enters the cell membrane as a result of membrane depolarization. The rate of fluorescence response of the dye to membrane potential change is usually slower than that of the styryl dye di-4-ANEPPS, but the fluorescence signal change for the former is significantly larger than for the latter dye. DiBAC₄(3) has applications in high-throughput drug screening.
<ul>
<li>Orange solid soluble in DMSO or DMF</li>
<li>Store at -20°C and protect from light</li>
<li>C₂₇H₄₀N₄O₆</li>
<li>MW: 519</li>
<li>[70363-83-6]</li>
</ul>