Descrition & Target

To be used as a cytotoxic control agent in the CellQuanti-BlueTM and CellQuanti-MTTTM Cell Viability Assay Kits. IC50 = 0.002 wt%. Kit size: (50mg) tests. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

Descrition & Target

DEAC [7-Diethylaminocoumarin-3-carboxylic acid] *CAS 50995-74-9*

Descrition & Target

DEAC,SE [7-Diethylaminocoumarin-3-carboxylic acid, succinimidyl ester] *CAS 139346-57-9*

Descrition & Target

100% O-Desmethylvenlafaxine

Descrition & Target

DEAC-dUTP *1 mM in Tris Buffer (pH 7.5)*

Descrition & Target

DEAC-dUTP (diethylaminocoumarin-dUTP) can be used to synthesize labeled DNA probes for in-situ hybridization, microarray or blotting techniques.  DEAC has absorption at 426 nm and emission at 480 nm.

Descrition & Target

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Descrition & Target

Di-4-ANEPPS is a fast-responding membrane potential dye. Changes in the membrane potential of the cell correlate with changes in the fluorescence excitation intensity of the dye.
<ul>
<li>&lamba;_Ex/&lamba; _Em(MeOH) = 496/705 nm</li>
<li>Orange red solid soluble in DMF, ethanol or DMSO</li>
<li>Store at 4°C and protect from light, especially in solution</li>
<li>C₂₈H₃₆N₂O₃S</li>
<li>MW: 481</li>
<li>[90134-00-2]</li>
</ul>

Descrition & Target

ANEPPS dyes are fast responding membrane potential dyes. 9689c5aa-6556-4b3c-b5d1-1e693715ba07 offers both Di-4-ANEPPS and Di-8-ANEPPS. Di-4-ANEPPS has the problem of being internalized in cells over long-term, so it is mainly used for short-term experiments. However, because Di-8-ANEPPS is more lipophilic, the dye is better retained in the outer leaflet of cell plasma membranes and thus more suitable for long-term membrane potential studies. Di-8-ANEPPS is also more photostable and less phototoxic than Di-4-ANEPPS.
<ul>
<li>&amp;lamba;Ex/&lamba;Em (MeOH) = 498/713 nm</li>
<li>Orange red solid soluble in DMF, ethanol or DMSO</li>
<li>Store at 4°C and Protect from light, especially when in solution</li>
<li>C₃₆H₅₂N₂O₃S</li>
<li>MW:593</li>
<li>[157134-53-7]</li>
</ul>

Descrition & Target

DiA 4-(4-Dihexadecylaminostyryl)-N-methylpyridinium iodide) is a green fluorescent membrane dye which diffuses much faster than DiO in cell membranes. DiA and DiI have been used together for two color membrane staining.
<ul>
<li>Red solid soluble in DMSO</li>
<li>Store at 4°C and protect from light, especially in solution</li>
<li>C₄₆H₇₉IN₂</li>
<li>MW: 787</li>
<li>[114041-00-8]</li>
</ul>

Descrition & Target

DiBAC₄(3) (Bis-(1,3-Dibarbituric acid)-trimethine oxanol) is a so-called translational membrane potential dye that redistributes within the cell membrane when membrane potential changes. The fluorescence of the dye is enhanced when the dye enters the cell membrane as a result of membrane depolarization. The rate of fluorescence response of the dye to membrane potential change is usually slower than that of the styryl dye di-4-ANEPPS, but the fluorescence signal change for the former is significantly larger than for the latter dye. DiBAC₄(3) has applications in high-throughput drug screening.
<ul>
<li>Orange solid soluble in DMSO or DMF</li>
<li>Store at -20°C and protect from light</li>
<li>C₂₇H₄₀N₄O₆</li>
<li>MW: 519</li>
<li>[70363-83-6]</li>
</ul>

Descrition & Target

DiD (DiIC18(5); 1,1'-dioctadecyl-3,3,3',3'- tetramethylindodicarbocyanine, 4-chlorobenzenesulfonate salt) is a lipophilic carbocyanine dye similar to DiI, but with longer absorption and emission wavelengths. DiR, DiD, DiI and Neuro-DiO can be used in combination for multicolor imaging. DiD is also available in CellBrite&trade; Red, a ready-to-use cell labeling solution.
<ul>
<li>&lamba;Ex/&lamba;Em (MeOH) = 644/663 nm</li>
<li>&epsilon;= 193,000</li>
<li>Dark blue solid soluble in ethanol, DMF and DMSO</li>
<li>Store at -20°C and protect from light</li>
<li>C₆₇H₁₀₃ClN₂O₃S</li>
<li>MW: 1052.1</li>
<li>[127274-91-3]</li>
</ul>